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Nuclear morphometry in differential diagnosis of renal oncocytoma and renal cell carcinoma
J P Castrén1, T Kuopio, M J Nurmi
1Department of Pathology, University of Turku, Finland.
The Journal of Urology
|October 1, 1995
Abstract
Purpose:
Morphometric distinction of renal oncocytoma and renal cell carcinoma was attempted.
Materials And Methods:
Nuclear morphometric measurements were done from sections of 16 histologically diagnosed renal oncocytomas and renal cell carcinoma controls (grade 1 or 2, stage T1 to 2N0M0).
Results:
Oncocytomas could be distinguished from carcinomas on the basis of nuclear morphometry in more than 80% of the cases. Especially, the shape descriptors (form factors) were significantly different between oncocytomas and carcinomas.
Conclusions:
Morphometrically determined nuclear shape descriptors can be used to support diagnostic decisions in problematic cases.