Related Experiment Video
Updated: Aug 10, 2026

An Immature Murine Model of Reversible Unilateral Ureteral Obstruction
Published on: April 4, 2025
Contradictory renal function measured with mercaptoacetyltriglycine diuretic renography in unilateral hydronephrosis
G R Gluckman1, L S Baskin, G A Bogaert
1Department of Urology, University of California School of Medicine, San Francisco 94143-0738, USA.
Purpose:
We studied apparently supranormal renal function in hydronephrotic kidneys, as measured by 99mtechnetium mercaptoacetyltriglycine renography.
Materials And Methods:
We retrospectively reviewed the clinical history, ultrasonography and renography of 29 children.
Results:
Of the 29 children 7 had greater than 50% relative function in the hydronephrotic kidney. This finding was independent of patient age, gender, degree of hydronephrosis or obstructive pattern. Of these 7 cases 6 occurred on the right side (p < 0.05 versus a large registry).
Conclusions:
In most cases supranormal renal function is caused by a technical problem, likely the inadequate background subtraction of mercaptoacetyltriglycine in the liver.
More Related Videos
Related Concept Videos
Factors Affecting Renal Clearance: Renal Impairment
One condition associated with renal failure is uremia. Uremia is characterized by impaired glomerular filtration and fluid accumulation in the body. This condition hinders the renal clearance of drugs, resulting in drug accumulation and potential...
Drug Dosing in Renal Diseases: Measurement of Glomerular Filtration Rate
Drug Dosing in Renal Diseases: Estimation of Glomerular Filtration Rate Based on Serum Creatinine Concentration
Serum Studies: Renal Function Tests
Imaging Studies V: Intravenous Urography and Retrograde Pyelography
Imaging Studies VII: Vascular Imaging

