Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

[Sleep and COPD]

E Weitzenblum1, A Chaouat, C Charpentier

  • 1Service de pneumologie, Hôpital de Hautepierre, Strasbourg.

La Revue Du Praticien
|May 15, 1995
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Management of women with abnormal cervical cytology: Update of French guidelines after the implementation of HPV screening.

European journal of obstetrics, gynecology, and reproductive biology·2025
Same author

Screening for precancerous anal lesions linked to human papillomaviruses: French recommendations for clinical practice.

Techniques in coloproctology·2024
Same author

SARS-CoV-2 viability and viral RNA persistence on microbiological agar plates.

The Journal of hospital infection·2022
Same author

[Nurse practitioners as key actors in pulmonary rehabilitation for chronic obstructive pulmonary disease].

Revue des maladies respiratoires·2022
Same author

Severe forms of COVID-19 among patients with chronic respiratory diseases: be attentive to the severity of the underlying respiratory impairment.

Respiratory medicine and research·2022
Same author

[The role of cardiac magnetic resonance imaging in pulmonary arterial hypertension and chronic thrombo-embolic pulmonary hypertension].

Revue des maladies respiratoires·2022
Same journal

[Prolonged fever].

La Revue du praticien·2026
Same journal

[Lower gastrointestinal bleeding].

La Revue du praticien·2026
Same journal

[Management of antiplatelet agents and oral anticoagulants in cases of gastrointestinal bleeding].

La Revue du praticien·2026
Same journal

[A history of child abuse intervention in the West].

La Revue du praticien·2026
Same journal

[Agranulocytose médicamenteuse].

La Revue du praticien·2026
Same journal

[Patient education in heart failure].

La Revue du praticien·2026
See all related articles

In chronic obstructive pulmonary disease (COPD) patients, hypoxemia worsens during sleep, especially REM sleep. Severe nocturnal oxygen desaturation indicates a need for oxygen therapy if daytime hypoxemia is present.

Area of Science:

  • Pulmonary Medicine
  • Sleep Medicine
  • Cardiology

Background:

  • Hypoxemia in COPD patients worsens during sleep, particularly during Rapid Eye Movement (REM) sleep.
  • Severe sleep-related oxygen desaturation is primarily seen in COPD patients with significant daytime hypoxemia.

Purpose of the Study:

  • To investigate the mechanisms and consequences of nocturnal hypoxemia in COPD patients.
  • To determine the indications for oxygen therapy in COPD patients experiencing sleep-related desaturation.

Main Methods:

  • Analysis of sleep-related oxygen saturation and blood gas levels in COPD patients.
  • Evaluation of the impact of nocturnal hypoxemia on pulmonary hypertension and cardiac arrhythmias.
  • Assessment of the association between COPD and sleep apnea syndrome on hypoxemia severity.

Related Experiment Videos

Main Results:

  • Nocturnal desaturation results from alveolar hypoventilation and ventilation-perfusion mismatch, with hypoventilation being predominant during REM sleep.
  • Sleep-related hypoxemia can trigger pulmonary hypertension and cardiac arrhythmias.
  • The combination of COPD and sleep apnea syndrome can lead to particularly severe hypoxemia.

Conclusions:

  • Severe nocturnal desaturation in COPD patients necessitates prolonged oxygen therapy, especially when accompanied by daytime hypoxemia (PaO2 < 55-60 mmHg).
  • The benefits of sleep-time-only oxygen therapy for nocturnal desaturators without significant daytime hypoxemia remain unproven.