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Recurrent Salmonella enteritidis meningitis in a patient with AIDS
A Gutiérrez1, R Teira, M Varona
1Department of Emergency Medicine, Hospital de Basurto, Bilbao, Spain.
Abstract:
The profound impairment of cellular immunity associated with HIV infection predisposes to salmonella infections with recurrent bacteremia as a well recognized opportunistic infection in patients with AIDS. However, salmonella meningitis is extremely rare in this group of patients and only 4 cases have been reported so far. We present 1 case of recurrent Salmonella enteritidis meningitis in an AIDS patient. The infection recurred despite prolonged antimicrobial therapy. Treatment of salmonella infections in AIDS patients may be very difficult and, in some cases, lifelong maintenance therapy may be required.
Insights
Recurrent Salmonella meningitis is rare in patients with acquired immunodeficiency syndrome (AIDS). This case highlights the challenges in treating Salmonella infections in immunocompromised individuals, often requiring long-term antimicrobial therapy.
Area of Science:
- Immunology
- Infectious Diseases
- Microbiology
Background:
- HIV infection profoundly impairs cellular immunity, increasing susceptibility to opportunistic infections.
- Salmonella bacteremia is a recognized opportunistic infection in patients with acquired immunodeficiency syndrome (AIDS).
Observation:
- Salmonella meningitis is exceptionally rare in AIDS patients, with only four cases previously reported.
- This report details a case of recurrent Salmonella enteritidis meningitis in an AIDS patient.
Findings:
- The patient experienced recurrent Salmonella meningitis despite extended antimicrobial treatment.
- The infection proved difficult to manage, underscoring treatment challenges in this population.
Implications:
- Managing Salmonella infections in AIDS patients can be complex and may necessitate lifelong maintenance antibiotic therapy.
- This case emphasizes the need for vigilant monitoring and potentially prolonged treatment strategies for invasive Salmonella infections in immunocompromised individuals.