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Therapeutic use of phospholipids in thrombocytopenic or thrombocytopathic patients
G V Dietrich1, D Söhngen, V Kretschmer
1Department of Transfusion Medicine and Hemostaseology, Klinikum Philips University, Marburg, Germany.
Eight thrombocytopenic/pathic patients received an intravenous infusion of phospholipids. In vitro bleeding test (Thrombostat 4000), thrombelastography, and resonance thrombography were performed in order to show the hemostatic effect. In none of the cases did phospholipids exert an effect comparable to platelet transfusion. Two patients, brother and sister, had a severe anaphylactoid reaction after the administration of phospholipids.
Eight thrombocytopenic/pathic patients received an intravenous infusion of phospholipids. In vitro bleeding test (Thrombostat 4000), thrombelastography, and resonance thrombography were performed in order to show the hemostatic effect. In none of the cases did phospholipids exert an effect comparable to platelet transfusion. Two patients, brother and sister, had a severe anaphylactoid reaction after the administration of phospholipids.