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Congenital dumbbell neuroblastoma
1Department of Orthopaedic Surgery, Akita University School of Medicine, Japan.
Spine
|June 1, 1995
Summary
Congenital dumbbell neuroblastoma can cause paraplegia in newborns. Early diagnosis and surgical decompression are crucial for better outcomes, though neurologic recovery remains a concern.
Area of Science:
- Pediatric Oncology
- Neuro-oncology
- Spinal Surgery
Background:
- Congenital dumbbell neuroblastoma with intraspinal extension is rare, with only 16 prior cases documented.
- This study reviews existing literature and presents two new cases.
Observation:
- Two infant patients with congenital dumbbell neuroblastoma causing paraplegia were diagnosed and surgically treated.
- Both patients survived without recurrence, but persistent incomplete paresis was noted.
Findings:
- Congenital dumbbell neuroblastoma has a high survival rate but is associated with poor neurological recovery.
- Spinal deformity occurred post-laminectomy in one patient, necessitating corrective surgery.
Implications:
- Early diagnosis via MRI and prompt spinal cord decompression are recommended for congenital dumbbell neuroblastoma.
- Multimodal treatment including chemotherapy is suggested to improve neurological outcomes in affected infants.