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[Development of biochemical and histopathological parameters in paracetamol overdose in experimental cholestasis]
G Ouvińa1, J C Perazzo, M Di Carlo
1Cátedra de Fisiopatología, Facultad de Farmacia y Bioquímica Universidad de Buenos Aires, Argentina.
Acta Gastroenterologica Latinoamericana
|January 1, 1995
Abstract:
The aim of the present paper is to determine the effect of Paracetamol (P) acute intoxication in cholestatic rats. Four groups of animals were considered: controls, controls intoxicated with P, rats intoxicated with P and cholestatic rats. Hepatic biochemical tests and liver histology were performed in every group. It is concluded that cholestatic rats intoxicated with P showed less Liver damage than in control groups.

