Multiple sclerosis. Sexual dysfunction and its response to medications

Area of Science:

• Neurology
• Sexual Medicine

Background:

• Sexual dysfunction is a prevalent and often overlooked issue in multiple sclerosis (MS).
• Understanding the specific nature and frequency of sexual dysfunction in MS is vital for comprehensive patient care.

Purpose of the Study:

• To determine the frequency and characteristics of sexual dysfunction in patients with multiple sclerosis (MS).
• To investigate the response of sexual dysfunction to various treatments, including medications, in MS patients.

Main Methods:

• A retrospective and prospective survey was conducted involving 65 female and 36 male patients diagnosed with MS.
• Data collected included patient-reported sexual activity, interest, specific dysfunctions, and associations with other health conditions.

Main Results:

• 63% of MS patients reported decreased sexual activity, and 35% reported reduced libido. 57 patients experienced sexual dysfunction, with men (78%) more affected than women (45%).
• Common issues included erectile dysfunction and decreased lubrication in men and women, respectively. Both sexes reported reduced sensation and difficulty achieving orgasm.
• Sexual dysfunction correlated with urinary problems and depression history. Corticosteroid treatment unexpectedly improved sexual functioning in some patients.

Conclusions:

• Sexual dysfunction is highly prevalent in multiple sclerosis (MS) and impacts quality of life.
• Identifying and addressing sexual dysfunction as part of MS care is essential.
• Potential treatments, including corticosteroids, may improve sexual functioning in MS patients.