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[Urinary infections following bladder catheterization]

J P Guignard, C L Fawer, A Kroener

Schweizerische Medizinische Wochenschrift

|December 6, 1975

Summary

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Prophylactic nitrofurantoin significantly reduced urinary tract infections (UTIs) after bladder catheterization during voiding cystourethrography (VCU). This preventative measure is justified for children undergoing VCU to prevent asymptomatic bacteriuria.

Area of Science:

Urology
Infectious Diseases
Pediatrics

Background:

Urinary tract infections (UTIs) are a potential complication following bladder catheterization.
Voiding cystourethrography (VCU) involves bladder catheterization, posing a risk for UTIs.

Purpose of the Study:

To investigate the incidence of UTIs after bladder catheterization during VCU.
To evaluate the efficacy of prophylactic nitrofurantoin in preventing UTIs in this context.

Main Methods:

A study involving 142 pediatric patients undergoing VCU.
Randomized groups: 71 received prophylactic nitrofurantoin (2 mg/kg daily for 4 days), 71 received no treatment.
Bacteriologic urine examination 4-9 days post-catheterization.

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Main Results:

Significant bacteriuria was detected in 5 of 71 untreated children (E. coli, Proteus, Klebsiella).
No cases of significant bacteriuria were observed in the 71 children who received prophylactic nitrofurantoin.
UTIs following VCU can be asymptomatic.

Conclusions:

The incidence of significant bacteriuria after VCU is notable.
Prophylactic nitrofurantoin administration is effective in preventing UTIs post-catheterization.
Preventative antibiotic therapy is warranted for children undergoing VCU.