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[Eosinophilic gastroenteritis]

F Salazar1, F Salazar

  • 1Dpto. de Gastroenterología, Clínica Ricardo Palma, Lima, Perú.

Revista De Gastroenterologia Del Peru : Organo Oficial De La Sociedad De Gastroenterologia Del Peru
|May 1, 1995
PubMed
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Eosinophilic Gastroenteritis (EGE) presents with varied symptoms and locations. This study highlights two distinct EGE cases, emphasizing diagnostic approaches and successful treatment with corticosteroids.

Area of Science:

  • Gastroenterology
  • Pathology
  • Immunology

Background:

  • Eosinophilic Gastroenteritis (EGE) is a rare condition of unknown cause.
  • It involves eosinophilic infiltration of the gastrointestinal tract wall, leading to diverse clinical presentations.
  • Peripheral eosinophilia often accompanies EGE.

Observation:

  • Two EGE cases with contrasting clinical courses are presented.
  • Case 1: Chronic illness with ascites and gastric outlet obstruction, requiring total gastrectomy.
  • Case 2: Acute presentation with abdominal symptoms and peripheral eosinophilia, diagnosed via endoscopic biopsy.

Findings:

  • Histologic infiltration patterns varied between cases, affecting different GI layers and segments.
  • Diagnostic work-up successfully excluded other causes of eosinophilia.

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  • Both patients achieved rapid clinical remission with low-dose prednisone therapy.

    • Implications:

    • EGE diagnosis and management require tailored approaches based on clinical presentation and infiltration patterns.
    • Corticosteroids can be effective in managing EGE, even in chronic or recurrent cases.
    • Further research into EGE etiology and long-term management is warranted.