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Effects of pentoxifylline on human sperm parameters in vitro
I Mladenovic1, S Micic, R M Pearson
1Institute for the Application of Nuclear Energy--INEP, Belgrade, Yugoslavia.
Journal of Assisted Reproduction and Genetics
|November 1, 1994
Abstract
Purpose:
Pentoxifylline was tested in three raising concentrations (0.7 mM/l, 1.5 mM/l, 3.6 mM/l) on human sperm cells in vitro.
Methods:
On 143 samples, we examined drug effect on motile sperm concentration, grade of their motility, acrosome reaction and membrane status.
Results:
Obtained results show improvement in motile sperm concentration, as well as in the grade of progression in the majority of samples.
Conclusions:
Spermatozoa membranes as well as occurrence of the acrosomal reaction were not affected by pentoxifylline.