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[Cancers in children in the Auvergne area: retrospective study from 1986 to 1991]
P Gembara1, P Dechelotte, F Chauvin
1Unité d'oncologie, Hôtel-Dieu CHRU, Clermont-Ferrand, France.
Insights
This study established a childhood cancer registry in the Auvergne region, identifying 153 cases between 1986-1991. The overall incidence rate for childhood cancers was 120.5 per million child-years.
Area of Science:
- Epidemiology
- Pediatric Oncology
- Cancer Registry
Context:
- Childhood cancers exhibit unique patterns necessitating specialized registries.
- Regional cancer data collection is crucial for understanding disease incidence.
- Previous epidemiological data for childhood cancers in the Auvergne region were limited.
Purpose:
- To establish a comprehensive childhood cancer registry in the Auvergne region.
- To determine the incidence rates of various childhood cancers.
- To provide a foundation for future etiological and survival studies.
Summary:
- A 6-year epidemiological study (1986-1991) in Auvergne identified 153 childhood cancer cases among 252,820 children.
- The overall age-standardized incidence rate was 120.5 cases per million child-years.
- Specific incidence rates were detailed for leukemias, central nervous system tumors, neuroblastomas, lymphomas, and other pediatric malignancies.
Impact:
- The created database serves as a vital resource for epidemiological research on childhood cancers.
- Facilitates studies on etiological factors, survival rates, and incidence trends.
- Informs public health strategies and resource allocation for pediatric cancer care in the region.
Background:
The specificity of childhood cancers led to the creation of regional childhood cancer registries. An epidemiological study of childhood cancers in the Auvergne area was carried out over a 6 year-period (1986-1991) in order to create a registry.
Population And Methods:
The population of our study was 252,820 children (0-15 years old), living in the Auvergne region. All malignant neoplasms were included together with brain tumours (whatever grading). Data were collected from medical and administrative sources.
Results:
The data of 153 cases were collected during this period. World age standardized overall incidence rate was 120.5 cases/milion/year. Age standardized incidence rates were: leukemias 37.6 (ALL 28.01), central nervous system tumours 18.34 (medulloblastomas 4.6, astrocytomas 4.6, ependymomas 3.8), lymphomas 10.0, neuroblastomas 18.6, soft tissue tumors 8.3, bone tumours 6.1 (Ewing's sarcomas 4.1, osteosarcomas 2.0), nephroblastomas 5.5, retinoblastomas 3.1, liver tumours 0.5 and others 0.5.
Conclusions:
Our data base in the Auvergne area might be a source of information for epidemiological studies on the role of etiological factors, the survival, the sequelae and the incidence trends.