Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Tidal volume maintenance during weaning with pressure support

R W Stroetz1, R D Hubmayr

  • 1Division of Pulmonary and Critical Care Medicine, Mayo Clinic, Rochester, Minnesota, USA.

American Journal of Respiratory and Critical Care Medicine
|September 1, 1995
PubMed
Summary

Gradually reducing pressure support (PS) in difficult-to-wean patients did not reliably predict respiratory failure. Patients unable to tolerate reduced support showed poorer respiratory mechanics, indicating this method is insufficient for identifying weaning success.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Safe mechanical ventilation in patients without acute respiratory distress syndrome (ARDS).

Minerva anestesiologica·2015
Same author

Calculation of shear stiffness in noise dominated magnetic resonance elastography data based on principal frequency estimation.

Physics in medicine and biology·2011
Same author

Noninvasive ultrasound image guided surface wave method for measuring the wave speed and estimating the elasticity of lungs: A feasibility study.

Ultrasonics·2010
Same author

Intraoperative ventilator settings and acute lung injury after elective surgery: a nested case control study.

Thorax·2008
Same author

Ventilator-associated lung injury: a search for better therapeutic targets.

The European respiratory journal·2007
Same author

Contractile response to colonic distention is influenced by oscillation frequency.

Neurogastroenterology and motility·2005

Area of Science:

  • Critical Care Medicine
  • Respiratory Physiology

Background:

  • Mechanical ventilation is crucial for patients with respiratory failure.
  • Weaning patients from mechanical ventilation can be challenging, especially in difficult-to-wean populations.
  • Identifying reliable methods to predict successful weaning is essential for patient outcomes.

Purpose of the Study:

  • To evaluate the effectiveness of gradual pressure support (PS) withdrawal in identifying difficult-to-wean patients.
  • To assess ventilatory response parameters in predicting weaning outcomes.
  • To determine if gradual PS reduction facilitates recognition of impending respiratory failure.

Main Methods:

  • Ventilation was measured in 31 difficult-to-wean patients.
  • Pressure support (PS) was reduced by 5 cm H2O every 20 minutes.

Related Experiment Videos

  • Patients were divided into a failure group (Group F) and a success group (Group S) based on distress criteria.

    • Main Results:

    • 14 of 31 patients (Group F) aborted weaning due to distress.
    • Group S patients had better static respiratory compliance (Cstat) and lower dead space to tidal volume ratio (Vd/Vt).
    • Tidal volume (VT) maintenance differed significantly between groups; Group S patients' VT stabilized at lower PS levels.

    Conclusions:

    • Gradual withdrawal of mechanical support does not reliably facilitate the recognition of impending respiratory failure.
    • Respiratory mechanics, such as Cstat and Vd/Vt, were better indicators of weaning success than ventilatory response parameters.
    • The rapid shallow breathing index showed limited value in predicting weaning outcome.