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Proteasome: a complex protease with a new fold and a distinct mechanism
1Macromolecular Structure Laboratory, NCI-Frederick Cancer Research and Development Center, MD 21702, USA.
Structure (London, England : 1993)
|May 15, 1995
Abstract:
The structure of the proteasome from Thermoplasma acidophilum introduces threonine proteases as a fifth class of proteolytic enzymes, and offers insights into the catalytic activity of this complicated piece of molecular machinery with its 14 active sites.