Borderline ovarian tumors. Case reports and review of literature

A borderline ovarian tumor or carcinoma of low malignant potential (LMP) may be defined as a tumor which possesses some, but not all, of the morphologic criteria of malignancy. The incidence ranges from 9% to 16.3% of the epithelial neoplasm and they are mainly at Stage I. Four cases of borderline ovarian tumor are described. Two (case 1 and case 2) given the patients' ages and the extent of the disease were treated with conservative therapy (monolateral ovariosalpingectomy), the other two, on the contrary, (case 3 and case 4) were treated with radical surgery. Given that, from current knowledge, non-invasive foci of a borderline type do not react to chemotherapy, no adjuvant chemotherapy was carried out. Antiblastic therapy is indicated only in sporadic cases of clearly invasive growth of the peritoneal foci. The follow-up, carried out every six months, was negative for partial or total recurrence of the disease, in all the patients.