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Pulmonary nodules due to Corynebacterium ulcerans
R B Dessau1, M Brandt-Christensen, O J Jensen
1Dept of Clinical Microbiology, Herlev University Hospital, Denmark.
The European Respiratory Journal
|April 1, 1995
Summary
A rare Corynebacterium ulcerans infection caused lung nodules in a 53-year-old male. Prompt penicillin treatment led to a complete recovery with no recurrence after two years.
Area of Science:
- Pulmonology
- Infectious Diseases
- Microbiology
Background:
- Pulmonary nodules can be indicative of metastatic disease, necessitating thorough investigation.
- Corynebacterium ulcerans is a bacterium known for causing infections, though typically less common in pulmonary presentations.
Observation:
- A 53-year-old male presented with a six-month history of cough and bilateral pulmonary nodules.
- Surgical resection of four nodules revealed granulomatous necrotizing inflammation.
- Histopathology confirmed the presence of Corynebacterium ulcerans, notably without diphtheria toxin production.
Findings:
- The patient received a one-week course of penicillin for the Corynebacterium ulcerans infection.
- Post-treatment follow-up for two years showed no signs of disease recurrence.
Implications:
- This case highlights Corynebacterium ulcerans as a potential, albeit rare, cause of pulmonary nodules.
- Early diagnosis and appropriate antibiotic therapy are crucial for successful management and favorable outcomes.
- Further research may elucidate the specific pathogenesis of pulmonary Corynebacterium ulcerans infections.