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Mycotoxins: regulations, quality assurance and reference materials

H P van Egmond1

  • 1Laboratory for Residue Analysis, National Institute of Public Health & Environmental Protection, Bilthoven, The Netherlands.

Food Additives and Contaminants
|May 1, 1995
PubMed
Summary

Ensuring reliable mycotoxin measurements is crucial for food safety regulations. Implementing Quality Assurance programs, including the use of certified reference materials, significantly improves the accuracy and consistency of laboratory results for mycotoxin analysis.

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Mycotoxin research·2013

Area of Science:

  • Food Science
  • Analytical Chemistry
  • Regulatory Science

Background:

  • Mycotoxin contamination in food and feed is a global concern, with approximately 60 countries implementing regulations.
  • Inconsistent rationales for setting mycotoxin limits and challenges in enforcement monitoring exist.
  • Interlaboratory studies reveal significant variability in mycotoxin analysis results, questioning laboratory reliability.

Purpose of the Study:

  • To highlight the importance of Quality Assurance (QA) in mycotoxin measurements.
  • To emphasize the role of certified reference materials (CRMs) in improving analytical reliability.
  • To discuss the development and availability of CRMs for various mycotoxins.

Main Methods:

  • Focus on the principles of Quality Assurance in laboratory operations.

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  • Discuss the characteristics and utility of certified reference materials.
  • Review existing and developing CRMs for mycotoxins like aflatoxins, deoxynivalenol, ochratoxin A, and fumonisins.

    • Main Results:

    • Quality Assurance programs enhance the scientific value and reliability of laboratory studies.
    • Certified reference materials are essential components of QA, providing stable, homogeneous standards.
    • Several CRMs for mycotoxins are available, with more under development, aiding accurate quantification.

    Conclusions:

    • Implementing robust Quality Assurance programs is vital for accurate mycotoxin testing.
    • The availability and use of certified reference materials are key to achieving reliable mycotoxin measurements.
    • Standardized methods and reference materials will support consistent global regulatory enforcement.