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Cloning and sequencing of a cDNA encoding the canine HSP27 protein
J K Larsen1, W T Gerthoffer, E Hickey
1Department of Pharmacology, University of Nevada School of Medicine, Reno, USA.
Gene
|August 19, 1995
Abstract:
The nucleotide (nt) sequence encoding a 27-kDa heat-shock protein (HSP27) was determined from cDNAs cloned from a canine smooth muscle library. The primary structure deduced from the nt sequence reveals a 209-amino-acid protein having 86-89% identity with human, mouse, rat and hamster small HSP. Similar to human HSP27, the canine protein contains three Ser residues that are potential MAPKAP kinase II substrates.