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Use of Interferon-γ Enzyme-linked Immunospot Assay to Characterize Novel T-cell Epitopes of Human Papillomavirus
Published on: March 8, 2012
[Diathermic loop treatment of subclinical cervical infection by human papilloma virus (HPV). Short-term
R H Milla Villeda1, T Gurrola Medrano
1Clínica de Colposcopia Privada, Facultad de Medicina, Universidad Juárez del Estado de Durango.
Abstract:
Multiple modalities of treatment have been employed since cervical subclinical papillomavirus (SPI) were discovered, with various degrees of success. The objective of this report is to assess the efficacy of the removal of cervical SPI by mean of LEEP in office conization. During the period from January 1992 and December 1993, 49 patients with histologically proven HPV infection were treated at the Private Colposcopic Clinic with LEEP. Patients ages ranged from 20 to 49 years old with average 36.1 years, mostly were parous woman. Satisfactory specimens suitable for histologic examination was obtained and in all cases margins of excisions appeared histologically clear of HPV infections patients discomfort was none or minimal in 45 patients (91.8%) and moderate in 4 (8.1%). There were 5 cases (10.2%) of postoperative haemorrhage and 3 cases (6.1%) of minimal cervical infections. The mean base of cone biopsy was 1.43 cm, and ranged from 1.0 to 3.0 cm. The overall cure rate of LEEP was 98% because there was only one confirmed case of treatment failures by loop conization. We concluded that this term results are satisfactory.
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