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Immediate skin-test reactivity in a general population sample

R A Barbee, M D Lebowitz, H C Thompson

Annals of Internal Medicine

|February 1, 1976

Summary

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Allergy prick tests reveal that allergic skin reactions are most common in adults under 30, with prevalence decreasing after age 50. These reactions were more frequent in higher socioeconomic groups.

Area of Science:

Immunology
Epidemiology

Background:

Allergic skin conditions affect a significant portion of the population.
Understanding the prevalence and distribution of allergic reactions is crucial for public health.

Purpose of the Study:

To determine the prevalence and distribution of allergic skin-test reactions in a general population.
To investigate the relationship between allergic reactivity and demographic factors such as age, sex, and socioeconomic status.

Main Methods:

Conducted allergy prick tests on 3101 subjects over 2 years of age.
Utilized common Tucson environmental allergens for testing.
Stratified subjects by age, sex, and socioeconomic status.

Main Results:

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No significant difference in reaction prevalence was observed between males and females.

Peak allergic reactivity (over 40%) occurred in the third decade of life, declining sharply after age 50.

Reactions were often multiple, reproducible, and more common in higher socioeconomic strata.

Conclusions:

Allergy prick tests are a valuable tool for assessing atopy (allergic predisposition).
Age and socioeconomic status are significant factors influencing allergic skin-test reaction prevalence.