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[Effect of selective activation of central serotoninergic systems on the course of the early post-traumatic period]
Abstract:
The central administration of the serotonin agonists of receptors type 1A (Campiron) and type 2 (1-(2,4,5-trimethoxy)-2-aminopropanome) was experimentally demonstrated to cause a significant decrease in mortality rates and cardiovascular disorders in white rats traumatized according to Kennon. This effect was realized by maximally activating the hypothalamo-neurohypophysis, hypothalamo-hypophysis-adrenocortical systems and blocking activation of the hypothalamo-hypophysis-thyroidal system.