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[Interaction between anti-infective agents and phagocytes]

M T Labro1

  • 1INSERM U294, Service d'Hématologie et d'Immunologie biologiques, CHU Bichat, Paris.

Presse Medicale (Paris, France : 1983)
|June 10, 1995
PubMed
Summary

Phagocytes and therapeutic agents are key to health. This review explores antimicrobial interactions with phagocytes, offering potential new treatments against microbial resistance.

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Area of Science:

  • Immunology
  • Microbiology
  • Pharmacology

Context:

  • Early research highlighted phagocyte-therapeutic agent cooperation for health.
  • Antimicrobial resistance necessitates novel therapeutic strategies.
  • Focus shifts to immunomodulatory drugs and host-microbe interplay.

Purpose:

  • To review interactions between antimicrobial agents and phagocytes.
  • To explore the role of phagocytes in the natural defense system.
  • To identify new therapeutic solutions beyond 2000.

Summary:

  • Phagocytes are crucial in the innate immune system.
  • Antimicrobial resistance is a growing global health concern.
  • This review examines how antimicrobials affect phagocyte function.
  • Potential for novel therapies by modulating host-microbe interactions.

Impact:

  • Understanding these interactions may lead to new treatments for infectious diseases.
  • This research could offer solutions to combat antimicrobial resistance.
  • Highlights the importance of the host's immune system in fighting infections.

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