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Cutaneous alternariosis

N B Pedersen, P A Mårdh, T Hallberg

    The British Journal of Dermatology
    |February 1, 1976
    PubMed
    Summary
    This summary is machine-generated.

    Cutaneous alternariosis, a fungal infection, presents as non-healing skin ulcers. This study details two cases, highlighting diagnostic methods and antifungal susceptibility for Alternaria.

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    Area of Science:

    • Mycology
    • Dermatology
    • Infectious Diseases

    Background:

    • Cutaneous alternariosis is a rare fungal infection caused by Alternaria species.
    • Patients often present with debilitating underlying conditions.
    • Skin lesions are typically characterized by non-healing ulcers with dry crusts.

    Purpose of the Study:

    • To present two cases of cutaneous alternariosis.
    • To review the literature on cutaneous alternariosis.
    • To describe methods for fungal isolation and antifungal susceptibility testing.

    Main Methods:

    • Clinical case presentation of two patients.
    • Histopathological examination of skin lesions.
    • Literature review of cutaneous alternariosis cases.

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  • Fungal isolation and identification of Alternaria.
  • Antimycotic drug susceptibility testing.

    • Main Results:

    • Two patients with cutaneous alternariosis were identified, both with primary debilitating diseases.
    • Macroscopic similarities in skin lesions were observed, but histological differences were noted.
    • A literature review identified ten additional cases of cutaneous alternariosis.
    • Methods for Alternaria isolation and its susceptibility to antimycotic drugs were detailed.

    Conclusions:

    • Cutaneous alternariosis requires careful diagnosis, considering clinical presentation and histopathology.
    • Underlying immunosuppression or debilitating diseases are common in affected individuals.
    • Understanding fungal susceptibility is crucial for effective treatment of cutaneous alternariosis.