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Synthesis and antimicrobial evaluation of 4-phenyl-3-isoquinolinoyl-hydrazones
F Vittorio1, G Ronsisvalle, A Marrazzo
1Istituto di Chimica Farmaceutica e Tossicologica, Università di Catania, Italy.
Farmaco (Societa Chimica Italiana : 1989)
|April 1, 1995
Abstract:
2-Methyl-1-oxo-1,2-dihydro-3-carbazoyl-4-phenylisoquinoline 2, 1-methoxy-7 and 1-chloro-3-carbazoyl-4-phenylisoquinoline 12 as well as a series of their 2-hydrazono-derivatives 3 a-i, 8 a-i and 14 a-i were synthesized and evaluated for their antibacterial and antifungal activities, in vitro. Compound 3 h was fairly active against Staphylococcus aureus, Staphylococcus epidermidis and streptococci group B.