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Effects of submaximal physical exercise and immobilization in bed on the adenine nucleotides concentration in human
A Buczyński1, K Kedziora-Kornatowska, J Kedziora
1Department of Medical Physiology, Institute of Fundamental Sciences, Military Medical Academy, Lódź, Poland.
Abstract:
The effects of submaximal physical exercise (75% VO2max) and one month immobilization in bed on the adenine nucleotides concentration in human blood platelets were studied and compared. We have shown that after submaximal exercise and after immobilization in bed the concentrations of adenine nucleotides in blood platelets mainly ATP and ADP were decreased and probably caused by the stimulation of platelet secretory process. Thrombin which stimulated the release of 58.2% +/- 1.5% of total adenine nucleotides from control platelets, liberated decreased amounts of nucleotides from platelets after physical exercise and after immobilization in bed (39.9 +/- 2.1% and 23.6 +/- 2.03% of total, respectively).