Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

A constant cathodic potential device for faradic stimulation of osteogenesis

C E Campbell1, D V Higginbotham, T J Baranowski

  • 1Department of Bioengineering, Clemson University, SC 29634, USA.

Medical Engineering & Physics
|July 1, 1995
PubMed
Summary

A new device maintains a constant cathodic potential for osteogenesis stimulation, preventing harmful electrochemical reactions. This technology ensures optimal current delivery for bone growth by controlling electrode potential.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Simulation of TTT Curves for Additively Manufactured Inconel 625.

Metallurgical and materials transactions. A. Physical metallurgy and materials science·2022
Same author

The Influence of Annealing Temperature and Time on the Formation of <i>δ</i>-Phase in Additively-Manufactured Inconel 625.

Metallurgical and materials transactions. A. Physical metallurgy and materials science·2019
Same author

The frustrated Heisenberg antiferromagnet on the honeycomb lattice: J1-J2 model.

Journal of physics. Condensed matter : an Institute of Physics journal·2012
Same author

Progression of infection and tumor development in damselfish.

Marine biotechnology (New York, N.Y.)·2004
Same author

A virus-like agent associated with neurofibromatosis in damselfish.

Diseases of aquatic organisms·2002
Same author

A dominant repression domain in Tbx3 mediates transcriptional repression and cell immortalization: relevance to mutations in Tbx3 that cause ulnar-mammary syndrome.

Human molecular genetics·2001

Area of Science:

  • Biomedical Engineering
  • Electrophysiology
  • Biomaterials

Background:

  • Osteogenesis stimulation requires precise control of electrical parameters.
  • Existing devices often lack control over cathodic potential, risking adverse electrochemical reactions.
  • Faradic stimulation of bone growth involves charge transfer, necessitating stable electrode potentials.

Purpose of the Study:

  • To design, develop, and validate a novel device for maintaining constant cathodic potential.
  • To enable optimal faradic stimulation of osteogenesis.
  • To prevent detrimental electrochemical effects associated with variable electrode potentials.

Main Methods:

  • Development of a device that automatically adjusts cathode-anode potential.
  • Testing the device's ability to maintain constant potential against a silver/silver chloride reference electrode.

Related Experiment Videos

  • Acute and chronic in-vivo testing with various electrodes until device failure.

    • Main Results:

    • The device successfully maintained a constant cathodic potential across diverse electrode configurations.
    • Consistent performance was observed during both acute and chronic testing phases.
    • The device prevented excessive cathodic potentials, mitigating risks of undesired electrochemical reactions.

    Conclusions:

    • The developed constant cathodic potential device is effective for osteogenesis stimulation.
    • This technology offers improved safety and efficacy compared to constant current devices.
    • Precise control of cathodic potential is crucial for successful faradic stimulation of bone regeneration.