Related Experiment Videos
[Stroke in pacemaker users for sinus node disease. Relevance of atrial function and clinical characteristics]
A V Mattioli1, E T Castellani, C Paolillo
1Cattedra di Cardiologia, Università degli Studi, Modena.
Cardiologia (Rome, Italy)
|February 1, 1995
Summary
Patients with sick sinus syndrome (SSS) have a higher stroke risk. Age over 65, prior cerebral ischemia, low atrial ejection force, and spontaneous echo contrast predict embolic events in SSS patients.
Area of Science:
- Cardiology
- Neurology
- Medical Imaging
Context:
- Sick sinus syndrome (SSS) is associated with a significant annual stroke incidence (6-10%).
- Pacemaker implantation is a common intervention for SSS.
- Understanding embolic risk factors in SSS patients is crucial for preventative strategies.
Purpose:
- To evaluate the prevalence of cerebral ischemia and peripheral embolism in SSS patients.
- To identify predictor factors for embolic events in pacemaker-dependent SSS patients.
- To compare outcomes between ventricular and physiological pacing modalities.
Summary:
- This study followed 80 SSS patients (40 ventricular, 40 physiological pacing) for 24 months, assessing embolic events via CT scans.
- Fifteen patients experienced endpoints including stroke, transient ischemic attack, and peripheral embolism.
- No significant difference in outcomes was observed between pacing groups.
Impact:
- Multivariate analysis identified age > 65, history of cerebral ischemia, low atrial ejection force, and spontaneous echo contrast as key predictors of embolic episodes.
- Findings aid in risk stratification and personalized management of SSS patients.
- Highlights the need for proactive monitoring and intervention in high-risk SSS individuals.