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Subcutaneous microvascular (capillary) calcification. Another basis for livedo-like skin changes?
D M Chapman1, A L Boskey, M Tesch
1Department of Anatomy and Neurobiology, Dalhousie University, Halifax, Nova Scotia, Canada.
Clinical and Experimental Dermatology
|May 1, 1995
Summary
A case study reveals that a morbidly obese woman with kidney failure experienced skin necrosis due to calcium and phosphorus deposits, identified as hydroxyapatite, in her subcutaneous tissue.
Area of Science:
- Nephrology
- Dermatology
- Pathology
Background:
- Morbid obesity and acute renal failure can lead to complex metabolic disturbances.
- Mineral imbalances, such as hyperphosphatemia and hypocalcemia, are common in renal failure.
- Subcutaneous complications can arise from severe metabolic derangements.