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Updated: Jul 28, 2026
06:24
Minimal Erythema Dose (MED) Testing
Published on: May 28, 2013
Oral terbinafine and erythema multiforme
1Department of Dermatology, St Bartholomew's Hospital, West Smithfield, London, UK.
Clinical and Experimental Dermatology
|May 1, 1995
Summary
Oral terbinafine, an antifungal medication, has been linked to a rare but serious skin reaction called erythema multiforme in two patients. This finding suggests a potential new adverse effect of terbinafine therapy.
Area of Science:
- Dermatology
- Pharmacology
Background:
- Terbinafine is a widely prescribed antifungal medication.
- Adverse drug reactions can significantly impact patient safety.
Observation:
- Two patients developed classical erythema multiforme.
- Erythema multiforme is a significant mucocutaneous reaction.
Findings:
- This is the first report associating oral terbinafine with erythema multiforme.
- A previous report linked terbinafine to Stevens-Johnson syndrome.
Implications:
- Clinicians should be aware of the potential for terbinafine-induced erythema multiforme.
- Further investigation into terbinafine's dermatologic adverse effects is warranted.
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