Related Experiment Videos
Cerebellar leptomeningeal astroglial heterotopia in neurofibromatosis type 1
M Kato1, S Takashima, S Houdou
1Department of Mental Retardation and Birth Defect Research, National Institute of Neuroscience, Tokyo, Japan.
Clinical Neuropathology
|May 1, 1995
Abstract:
Leptomeningeal astroglial heterotopia (LAH) was found in the cerebellum of 2 patients with neurofibromatosis type 1 (NF 1). This LAH was clearly and widely demonstrated with glial fibrillary acidic protein (GFAP) immunohistochemistry and was connected with parenchymal astroglial fibers. These findings suggest that NF 1 involves the dysplasia or overgrowth of astrocytes in the cerebellar leptomeninges.