Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Birth weight: nature or nurture?

A A Brooks1, M R Johnson, P J Steer

  • 1Academic Department of Obstetrics and Gynaecology, Chelsea and Westminster Hospital, London, UK.

Early Human Development
|May 12, 1995
PubMed
Summary

Environmental factors, specifically the recipient

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Cardiovascular outcomes and aortic growth in pregnant women with Turner syndrome: data from the ESC EORP Registry Of Pregnancy And Cardiac disease (ROPAC) III.

European journal of preventive cardiology·2025
Same author

Pregnancy outcomes in women with heritable thoracic aortic disease: data from the EORP ESC registry of pregnancy and cardiac disease (ROPAC) III.

European heart journal. Quality of care & clinical outcomes·2025
Same author

Carbetocin as a uterotonic in a parturient with a Fontan circulation.

Anaesthesia reports·2024
Same author

Reproductive health in adults with congenital heart disease: a review on fertility, sexual health, assisted reproductive technology and contraception.

Expert review of cardiovascular therapy·2023
Same author

Fetal growth and fetoplacental circulation in pregnancies following bariatric surgery: a prospective study.

BJOG : an international journal of obstetrics and gynaecology·2020
Same author

Human labour is associated with altered regulatory T cell function and maternal immune activation.

Clinical and experimental immunology·2019

Area of Science:

  • Reproductive Medicine
  • Genetics
  • Maternal-Fetal Medicine

Background:

  • Ovum donation involves using eggs from a donor to achieve pregnancy.
  • Understanding factors influencing birth weight is crucial for neonatal health.
  • Distinguishing genetic from environmental influences in assisted reproduction is complex.

Purpose of the Study:

  • To determine the relative importance of genetic versus environmental factors in influencing birth weight in ovum donation pregnancies.
  • To assess the impact of donor characteristics and recipient characteristics on the birth weight of the offspring.

Main Methods:

  • Analysis of data from 62 ovum donation cases.
  • Statistical examination of the correlation between donor attributes (weight, personal birth weight, offspring birth weight) and recipient attributes (weight) with the resulting birth weight.
  • Control for gestational age as a known determinant of birth weight.

Main Results:

  • Gestational age and recipient's pre-pregnancy weight were significant predictors of birth weight.
  • No significant correlation was found between donor's weight, her own birth weight, or her children's birth weight and the birth weight of the ovum donation offspring.
  • These findings suggest a stronger environmental influence from the recipient.

Conclusions:

  • The maternal environment plays a more significant role than genetic factors in determining birth weight in ovum donation.
  • Recipient's physiological state (weight) and pregnancy duration (gestational age) are key determinants.
  • This highlights the importance of maternal health and gestational management in optimizing fetal growth in ovum donation contexts.

Related Experiment Videos