A case of severe ovarian hyperstimulation in a healthy oocyte donor
J Halme1, S K Toma, L M Talbert
1North Carolina Center for Reproductive Medicine, Cary 27511, USA.
Objective:
To report an unexpected case of severe ovarian hyperstimulation syndrome (OHSS) and to compare E2 levels and number of follicles to other oocyte donors.
Setting:
Private assisted reproduction technology center.
Patients:
Healthy oocyte donors with normal menstrual cyclicity.
Interventions:
Prophylactic and therapeutic use of human serum albumin infusions.
Main Outcome Measure:
The clinical development of signs and symptoms of severe OHSS.
Results:
More than 60% of other oocyte donors had higher E2 levels and 12% had higher number of follicles without associated OHSS.
Conclusion:
The risk of developing severe OHSS cannot be predicted accurately to be low even in the absence of "risk factors."
