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Standard biopsy forceps versus large-capacity forceps with and without needle
D E Bernstein1, J S Barkin, D K Reiner
1University of Miami, School of Medicine/Mt. Sinai Medical Center, Division of Gastroenterology, Miami Beach, FL 33140, USA.
Gastrointestinal Endoscopy
|June 1, 1995
Summary
Large capacity biopsy forceps yield larger gastric tissue samples compared to standard forceps. Needle versions of forceps obtained deeper biopsies, but crush artifact was similar across all types.
Area of Science:
- Gastroenterology
- Endoscopic Procedures
- Surgical Instrumentation
Background:
- Endoscopic biopsy forceps are crucial for obtaining tissue samples during gastrointestinal endoscopy.
- Variations in forceps design, including needle inclusion and capacity, may influence tissue yield and quality.
Purpose of the Study:
- To prospectively compare gastric tissue quality and quantity from needle vs. non-needle standard biopsy forceps and novel large-capacity forceps.
- To evaluate the impact of forceps design on specimen size, depth, and crush artifact.
Main Methods:
- A prospective randomized study involving 50 patients undergoing endoscopy.
- Comparison of tissue samples obtained using standard and large-capacity biopsy forceps, with and without needles.
Main Results:
- Large-capacity forceps (both needle and non-needle) produced significantly larger specimens than standard forceps (p = 0.02).
- Needle versions of forceps consistently obtained deeper tissue samples than non-needle versions.
- No significant difference in crush artifact was observed between any of the forceps types.
Conclusions:
- Large-capacity biopsy forceps are superior to standard forceps in terms of specimen quantity.
- Needle inclusion enhances biopsy depth, irrespective of forceps capacity.
- Further research with larger cohorts is needed to ascertain the diagnostic implications of these findings.