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Detection of Low Copy Number Integrated Viral DNA Formed by In Vitro Hepatitis B Infection
Published on: November 7, 2018
Hepatitis B virus superinfection in a patient with chronic hepatitis C receiving alpha-interferon treatment
G Teuber1, H P Dienes, K H Meyer zum Büschenfelde
1Department of Medicine I, Johannes Gutenberg Universität Mainz, Germany.
Abstract:
We report on a patient with chronic hepatitis C who developed acute hepatitis B during interferon alpha treatment. However, our patient promptly eliminated HBsAg and had a sustained complete response to interferon, even 6 months after the end of treatment. Acute hepatitis B superinfection in patients with chronic hepatitis C is a rarely observed event. The natural course of these patients is unknown. In our case it may be speculated that alpha-interferon treatment contributed to the prompt elimination of HBsAg from the serum.
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