CXT: a programme for analysis of linear dynamic systems in the frequency domain

Area of Science:

• * Systems analysis
• * Computational modeling
• * Biomedical engineering

Background:

• * Linear dynamic systems analysis is crucial in various scientific fields.
• * Modeling complex biological systems requires robust computational tools.
• * Frequency response methods offer a powerful approach to system identification.

Purpose of the Study:

• * To introduce and demonstrate the CXT (CompleX Tools for Linear Dynamic System Analysis) computer program.
• * To showcase the application of the frequency response method for system modeling.
• * To illustrate the program's utility in analyzing biological systems.

Main Methods:

• * Development of the CXT program utilizing the frequency response method.
• * Approximation of system frequency response using frequency-dependent polynomials.
• * Menu-driven software design for interactive or automatic operation under DOS/WINDOWS.
• * Data input via keyboard or file, with output to screen, printer, or file.

Main Results:

• * CXT successfully models linear or linearized dynamic systems, including those with serial/parallel subsystems and time delays.
• * The program provides versatile data handling and output options (tables, plots).
• * Numerical examples from pharmacokinetics and indocyanine green liver function tests validate the program's applicability.

Conclusions:

• * CXT is a general-purpose tool for analyzing linear dynamic systems, particularly applicable to biological modeling.
• * The frequency response method, as implemented in CXT, provides an effective approach for system identification and analysis.
• * The software's user-friendly interface and broad applicability make it valuable for researchers in diverse fields.