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A bioactive tetraprenylphenol from Lactarius lignyotus
G Vidari1, P Vita-Finzi, A M Zanocchi
1Dipartimento di Chimica Organica, Università di Pavia, Italy.
Journal of Natural Products
|June 1, 1995
Abstract:
2-Geranylgeranyl-1,4-dihydroxybenzene [1] and a mixture of fatty acid esters of this phenol were isolated from the fruiting bodies of Lactarius lignyotus. Compound 1 was highly active in the brine shrimp test and showed significant inhibitory activity on DNA, RNA, and protein synthesis in HeLa and HL-60 cell lines.