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Related Experiment Videos

Primary central nervous system lymphoma presenting as autonomic dysfunction

D M Ficker1, J E Hammack

  • 1Department of Neurology, Mayo Clinic, Rochester, Minnesota, USA.

Journal of Neuro-Oncology
|January 1, 1995
PubMed
Summary
This summary is machine-generated.

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Primary central nervous system lymphoma (PCNSL) can cause dysautonomia, a disorder affecting the autonomic nervous system. This case highlights PCNSL as a potential cause of paraneoplastic syndromes presenting with autonomic dysfunction.

Area of Science:

  • Neurology
  • Oncology

Background:

  • Primary central nervous system lymphoma (PCNSL) is a rare extranodal non-Hodgkin lymphoma.
  • Dysautonomia, or autonomic dysfunction, affects the regulation of involuntary bodily functions.

Observation:

  • A patient presented with subacute onset of dysautonomia.
  • Autonomic testing revealed peripheral autonomic neuropathy.
  • Magnetic resonance imaging (MRI) showed brainstem involvement.

Findings:

  • The observed autonomic dysfunction in this patient is potentially linked to a paraneoplastic syndrome.
  • The findings suggest a possible association between PCNSL and the development of dysautonomia.

Implications:

  • PCNSL should be considered in the differential diagnosis for patients presenting with unexplained dysautonomia.

Related Experiment Videos

  • This case broadens the understanding of potential neurological manifestations of PCNSL.
  • Further research may elucidate the mechanisms linking PCNSL and paraneoplastic autonomic neuropathy.