Inhibitors of neprilysin: design, pharmacological and clinical applications

Binding properties of a highly potent and selective iodinated aminopeptidase N inhibitor appropriate for radioautography.

FEBS letters·2000

Effects of cationic charge on three-dimensional structures of intercalative complexes: structure of a bis-intercalated DNA complex solved by MAD phasing.

Current medicinal chemistry·2000

The HIV-1 viral protein R induces apoptosis via a direct effect on the mitochondrial permeability transition pore.

The Journal of experimental medicine·2000

Nucleic acid sequence discrimination by the HIV-1 nucleocapsid protein NCp7: a fluorescence study.

Biochemistry·1999

Investigation of subsite preferences in aminopeptidase A (EC 3.4.11.7) led to the design of the first highly potent and selective inhibitors of this enzyme.

Journal of medicinal chemistry·1999

In vitro evidence for the interaction of tRNA(3)(Lys) with U3 during the first strand transfer of HIV-1 reverse transcription.

Nucleic acids research·1999

Comparative methods for recombinant production and characterization of 1-deoxy-D-xylulose-5-phosphate synthase from bacterial and apicomplexan sources.

Methods in enzymology·2026

Current methods and applications in the study of 1-Deoxy-D-xylulose 5-phosphate synthase (DXPS).

Methods in enzymology·2026

Thiamine pyrophosphate-dependent enzymes in Toxoplasma gondii and functional significance of an apicoplast-localized pyruvate dehydrogenase.

Methods in enzymology·2026

Biochemical and cryo-EM studies of the pyruvate dehydrogenase complex from native cell extracts.

Methods in enzymology·2026

Synthesis of phosphonate and phosphinate analogs of 2-oxo acids for site-specific inhibition of thiamine-diphosphate-dependent dehydrogenases of 2-oxo acids in vivo.

Methods in enzymology·2026

Use of dihydroxyacetone synthase for the assimilation of methanol in E. coli.

Methods in enzymology·2026

Analytical Detection and Sample Preparation Techniques for Selected New Psychoactive Substances: Advances, Critical Limitations, and Future Perspectives.

Critical reviews in analytical chemistry·2026

Capsaicin suppresses microglial inflammation through TRPV1-SSR4 interaction.

Translational neurodegeneration·2026

Context-dependent vascular effects of platycodin D: inhibition of neointima formation but aggravation of atherosclerosis with involvement of mTORC1 signaling.

Acta pharmacologica Sinica·2026

Gelsemine attenuates neuropathic pain in a rat model of sciatic nerve chronic constriction injury.

Molecular pain·2026

Characterisation and anti-cancer activities of polysaccharides obtained from Punica granatum L. by different extraction methods.

Natural product research·2026

Chemically Modified ω-Agatoxin IVA Enables Exploration of P/Q-Type Voltage-Dependent Calcium Channels.

Biochemistry·2026

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Inhibitors of neprilysin: design, pharmacological and clinical applications

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Binding properties of a highly potent and selective iodinated aminopeptidase N inhibitor appropriate for radioautography.

Effects of cationic charge on three-dimensional structures of intercalative complexes: structure of a bis-intercalated DNA complex solved by MAD phasing.

The HIV-1 viral protein R induces apoptosis via a direct effect on the mitochondrial permeability transition pore.

Nucleic acid sequence discrimination by the HIV-1 nucleocapsid protein NCp7: a fluorescence study.

Investigation of subsite preferences in aminopeptidase A (EC 3.4.11.7) led to the design of the first highly potent and selective inhibitors of this enzyme.

In vitro evidence for the interaction of tRNA(3)(Lys) with U3 during the first strand transfer of HIV-1 reverse transcription.

Comparative methods for recombinant production and characterization of 1-deoxy-D-xylulose-5-phosphate synthase from bacterial and apicomplexan sources.

Current methods and applications in the study of 1-Deoxy-D-xylulose 5-phosphate synthase (DXPS).

Thiamine pyrophosphate-dependent enzymes in Toxoplasma gondii and functional significance of an apicoplast-localized pyruvate dehydrogenase.

Biochemical and cryo-EM studies of the pyruvate dehydrogenase complex from native cell extracts.

Synthesis of phosphonate and phosphinate analogs of 2-oxo acids for site-specific inhibition of thiamine-diphosphate-dependent dehydrogenases of 2-oxo acids in vivo.

Use of dihydroxyacetone synthase for the assimilation of methanol in E. coli.

Analytical Detection and Sample Preparation Techniques for Selected New Psychoactive Substances: Advances, Critical Limitations, and Future Perspectives.

Capsaicin suppresses microglial inflammation through TRPV1-SSR4 interaction.

Context-dependent vascular effects of platycodin D: inhibition of neointima formation but aggravation of atherosclerosis with involvement of mTORC1 signaling.

Gelsemine attenuates neuropathic pain in a rat model of sciatic nerve chronic constriction injury.

Characterisation and anti-cancer activities of polysaccharides obtained from Punica granatum L. by different extraction methods.

Chemically Modified ω-Agatoxin IVA Enables Exploration of P/Q-Type Voltage-Dependent Calcium Channels.

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Inhibitors of neprilysin: design, pharmacological and clinical applications

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