[Current role of abdomino-perineal amputation]

In Italy 6.5% of cancer deaths can be attributed to localized colorectal cancer of which rectal cancer alone accounts for 33%. The introduction of mechanical staplers and new techniques (colo-anal anastomosis) into colon surgery has led to a drastic reduction in indications for Miles' operation in favour of techniques which aim to conserve the sphincter. From October 1987 to March 1991 the Surgical Clinical of the Ospedale Maggiore in Novara operated 75 patients with rectal cancer. Twenty-eight patients underwent APA (abdominoperineal amputation) whereas 47 underwent conservative surgery, referred to as SSR (sphincter-saving resection). Of the 28 APA patients, 19 revealed a localisation in the lower rectum (0-5), 7 in the mid rectum (6-8) and 2 in the upper rectum (9-15). In the latter two cases the considerable size of the tumour mass and the extraparietal diffusion of the tumour led the authors to prefer APA rather than SSR. In SSR the minimum distal safety margin from the tumour was 2 cm, whereas the mean distance of the tumour from the anal margin in APP patients was 4 cm, and that in SSR patients 11 cm. The stage of cancer was not taken into consideration when choosing the type of surgery. Postoperative mortality was 3.5% for APA and 2% for SSR. The overall incidence of recidivation was 20%, equivalent to 11 patients. Recidivation was found to be more frequent in the lower rectum (6 cases) compared to the upper rectum (1 case).(ABSTRACT TRUNCATED AT 250 WORDS)