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Kaposi sarcoma presenting as a vulvar mass

M A Macasaet1, A Duerr, W Thelmo

  • 1Department of Obstetrics and Gynecology, SUNY Health Science Center, Brooklyn, USA.

Obstetrics and Gynecology
|October 1, 1995
PubMed
Summary

This case study highlights HIV-associated Kaposi sarcoma presenting as a vulvar mass in a woman. It emphasizes the importance of considering Kaposi sarcoma in the differential diagnosis of vulvar lesions.

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Area of Science:

  • Oncology
  • Infectious Diseases
  • Dermatology

Background:

  • Kaposi sarcoma is a common AIDS-related malignancy, predominantly seen in men.
  • Genital Kaposi sarcoma in women with AIDS is rare, particularly in the United States.
  • Previous reports of genital Kaposi sarcoma in the US did not involve human immunodeficiency virus (HIV)-positive individuals.

Observation:

  • A 29-year-old woman with a history of AIDS presented with vulvar pain, discharge, and a mass.
  • Biopsy confirmed Kaposi sarcoma of the vulva.
  • Viral analysis detected herpes simplex virus type 2 and human papillomavirus 26 in the tumor.

Findings:

  • The case presents a rare instance of HIV-associated Kaposi sarcoma manifesting as a vulvar lesion.
  • Co-infection with herpes simplex virus type 2 and human papillomavirus 26 was noted.

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Implications:

  • This case underscores the need for healthcare providers to consider Kaposi sarcoma in the differential diagnosis of vulvar lesions.
  • Early recognition and diagnosis are crucial for managing HIV-associated malignancies.
  • Highlights the global occurrence of HIV-associated genital Kaposi sarcoma.