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[The role of mitochondrial DNA in the origin of regular trisomy 21]

Tsitologiia I Genetika

|May 1, 1995

Abstract:

Hypothesis about cytoplasmic heredity and the influence of mitochondrial DNA mutations on the pathogenesis of 21 trisomy has been suggested. It explains the association of increased risk of trisomy with the maternal age, malignant diseases, autoimmune processes, other pathologies and with the origin of paternal 21 chromosome.

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