[The walking-through phenomenon in arterial occlusive disease]

In order to assess the metabolic effects of walking-through phenomenon during treadmill exercise the fluctuations of lactate and pyruvate concentration in arterial and popliteal venous blood and the changes in the lactate pyruvate ratio were studied in seven patients with arterial occlusive disease. During exercise, significant differences in venous lactate, lactate pyruvate ratio and arterial venous differences in lactate were found in patients with walking-through phenomenon. It is concluded that the rate of anaerobic glycolysis is reduced in patients with walking-through phenomenon.