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A xeroderma pigmentosum complementation group A related gene: confirmation using monoclonal antibodies against the

T Mori1, T L Rinaldy, R S Athwal

  • 1Nara Medical University, RI Center, Japan.

Mutation Research
|January 1, 1993
PubMed

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Cells are regularly exposed to mutagens—factors in the environment that can damage DNA and generate mutations. UV radiation is one of the most common mutagens and is estimated to introduce a significant number of changes in DNA. These include bends or kinks in the structure, which can block DNA replication or transcription. If these errors are not fixed, the damage can cause mutations, which in turn can result in cancer or disease depending on which sequences are...