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Published on: April 11, 2014
Radioprotective effect of vitamins C and E
S M el-Nahas1, F E Mattar, A A Mohamed
1Cell Biology, National Research Centre, Dokki, Cairo, Egypt.
Abstract:
Albino rats were treated with aqueous vitamin C solution and vitamin E solution dissolved in olive oil at two concentrations, 100 and 300 mg/kg/day, for 6 months. Some of the animals were then subjected to whole-body irradiation. Chromosomal aberrations and mitotic activity in non-irradiated and irradiated groups were recorded. Both vitamins were found to be non-mutagenic. Vitamin C exerted a radioprotective effect but vitamin E was not radioprotective and it suppressed the radioprotection otherwise produced by olive oil.
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