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Fazarabine: a report of response in a patient with multiply relapsed embryonal cell carcinoma
P G Johnston1, D Kleiner, K H Cowan
1Medicine Branch, National Cancer Institute, National Institutes of Health, Bethesda, Maryland 20889.
American Journal of Clinical Oncology
|February 1, 1993
Abstract:
This report describes a patient with multiply relapsed and advanced metastatic embryonal cell carcinoma who achieved a pathological partial remission (PR) following treatment with a Phase I chemotherapeutic agent, arabinosyl-5-azacytosine (Ara-AC), followed by orchiectomy. The antimetabolic Ara-AC is worthy of further study in patients with germ-cell tumors. It would appear that the antimetabolite Ara-AC may have significant activity in patients with germ-cell tumors.