Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Bovine myocardial epithelial inclusions

D C Baker1, S P Schmidt, K A Langheinrich

  • 1Department of Pathology, Colorado State University, Ft. Collins.

Veterinary Pathology
|January 1, 1993
PubMed
Summary

This study examined myocardial epithelial masses in cattle hearts using various microscopic and staining techniques. These masses likely represent misplaced endodermal tissue from early development.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

SAGES masters program: the top 10 seminal articles for the laparoscopic left and sigmoid colectomy pathway for complex disease.

Surgical endoscopy·2023
Same author

Community Priority setting for Fetal Alcohol Spectrum Disorder Research in Australia.

International journal of population data science·2021
Same author

Prevalence of recreational drug use reported by men who have sex with men attending sexual health clinics in Manchester, UK.

International journal of STD & AIDS·2017
Same author

Preclinical safety and efficacy of andexanet alfa in animal models.

Journal of thrombosis and haemostasis : JTH·2017
Same author

Correction of protruding ears: A 20-year retrospective.

Aesthetic plastic surgery·2013
Same author

Environmental pathobiology and global opportunities.

Veterinary pathology·2013

Area of Science:

  • Veterinary Pathology
  • Comparative Pathology
  • Histology

Background:

  • Myocardial epithelial masses are rare lesions found in animal hearts.
  • Understanding their origin and characteristics is crucial for veterinary diagnostics.

Purpose of the Study:

  • To characterize the histological, histochemical, and immunohistochemical features of myocardial epithelial masses in cattle.
  • To compare these bovine lesions with similar findings in other species.
  • To elucidate the potential origin of these myocardial tumors.

Main Methods:

  • Light microscopy, histochemistry, immunohistochemistry, and ultrastructural examination were employed.
  • Tissues from ten cattle hearts were analyzed, including samples from slaughterhouses and deceased calves.
  • Standard staining techniques (PAS, Alcian blue, colloidal iron) and immunohistochemical markers (cytokeratin, vimentin, CEA, desmin) were utilized.

Main Results:

  • Bovine myocardial masses were well-circumscribed lesions in the left ventricle, composed of squamous to cuboidal epithelial cells forming tubular/acinar structures.
  • Ultrastructural analysis revealed epithelial cells with sparse microvilli, tight junctions, and perinuclear filaments.
  • Immunohistochemistry showed positive staining for cytokeratin (all samples), vimentin (3/8), and CEA (3/8), but negative for desmin.

Conclusions:

  • The myocardial epithelial tumors in cattle exhibit characteristics consistent with endodermal rests.
  • These findings suggest a developmental origin due to misplaced tissue during organogenesis.
  • The study contributes to the understanding of rare cardiac lesions in cattle.

Related Experiment Videos