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An association between fetal abdominal wall defects and elevated levels of human chorionic gonadotropin in
D Schmidt1, E Rose, F Greenberg
1Institute for Molecular Genetics, Baylor College of Medicine, Houston, TX 77030.
Prenatal Diagnosis
|January 1, 1993
Abstract:
We analysed maternal serum human chorionic gonadotropin (hCG) in 16 pregnancies with fetal abdominal wall defects previously identified prenatally by elevated maternal serum alpha-fetoprotein (AFP) or at birth. The AFP levels had a mean of 6.38 MOM (range 0.34-15.65), as expected with these defects. The hCG levels had a mean of 1.82 MOM (range 0.23-4.11). The hCG levels in five pregnancies (31.25 per cent) were above 2.30 MOM. Elevated levels of hCG may be associated with fetal abdominal wall defects.