Cathepsin E in antigen-presenting Langerhans and interdigitating reticulum cells. Its possible role in antigen

E Solcia1, M Paulli, E Silini

  • 1Dipartimento di Patologia Umana ed Ereditaria, I Facoltà di Medicina e Chirurgia, Università di Pavia ed I.R.C.C.S. Policlinico S. Matteo, Italy.

Summary

Cathepsin E, an aspartic proteinase, is found in skin and lymph node immune cells like Langerhans cells, but not macrophages. Its location suggests a role in antigen processing.

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