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Is there a role for MACOP-B in the treatment of diffuse large cell lymphoma?
1Department of Medical Oncology, B.C. Cancer Agency, Vancouver, Canada.
Leukemia & Lymphoma
|January 1, 1993
Abstract:
Between 1981 and 1986, 126 patients with advanced stage, large cell lymphoma were treated with MACOP-B chemotherapy. Their six-year failure-free and overall survival is 52% and 62% respectively. Eighty-eight patients aged 60 or less had an excellent six year overall survival of 68%. The outcome for various subsets of patients is analysed according to the number of adverse prognostic factors including age, stage, lactic dehydrogenase level and number of extra nodal sites.