The acute effects of Dramamine on uterine contractability during labor

The acute effects of intravenously administered Dramamine or placebo on uterine activity were studied in 32 primigravida patients during the active phase of spontaneous labor. Uterine activity was monitored by invasive quantitative techniques. The results showed no change in uterine activity in the placebo group, but there was a significant increase in activity in the Dramamaine-treated women. The increased activity was primarily the result of an increase in the frequency of contractions.